In vitro evaluation of the interaction between tea extracts and penicillin G against staphylococcus aureus

The herb-drug interaction between tea (Carmelia sinensis) extract and penicillin G (Pen G) was investigated against three strains of Staphylococcus aureus using pair combinations in an in vitro decimal assay for additivity test. Results showed that the interactions between penicillin G and tea extracts were mainly additive against the three strains of S. aureus. This suggests that the concomitant administration of tea and Pen G may not impair the antimicrobial activity of Pen G.