Knockout of the CCCH zinc finger protein TcZC3H31 blocks Trypanosoma cruzi differentiation into the infective metacyclic form

T. cruzi knockout for the TcZC3H31 gene (TcZC3H31 KO) is incapable, both in vitro and in vivo, to differentiate into the metacyclic trypomastigote form. [Display omitted] •T. cruzi insect forms have higher levels of the CCCH zinc finger protein TcZC3H31.•TcZC3H31 overexpression significantly increas...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular and biochemical parasitology 2018-04, Vol.221, p.1-9
Hauptverfasser:	Alcantara, Monica Visnieski, Kessler, Rafael Luis, Gonçalves, Rosana Elisa Gonçalves, Marliére, Newmar Pinto, Guarneri, Alessandra Aparecida, Picchi, Gisele Fernanda Assine, Fragoso, Stenio Perdigão
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CCCH zinc finger protein Gene Expression Profiling Gene Knockout Techniques Insecta Metacyclogenesis Protozoan Proteins - genetics Protozoan Proteins - metabolism RNA binding protein RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism Trypanosoma cruzi Trypanosoma cruzi - cytology Trypanosoma cruzi - genetics Trypanosoma cruzi - growth & development Zinc Fingers
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!