Effect of ketorolac tromethamine on lymph circulation, contractile activity of the lymphangion and lymphatic microvessels, and cellular composition and toxicity of the lymph during fever

Single parenteral administration of ketorolac tromethamine produced a lymphotropic effect, which was manifested in acceleration of lymph flow in the thoracic duct and increase in contractile activity of the wall and valves in mesenteric lymphatic microvessels of rats with fever. These changes improv...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2005-10, Vol.140 (4), p.400-402
Hauptverfasser:	Khafiz'yanova, R K, Aleeva, G N, Mukhutdinov, D A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Fever - drug therapy Fever - immunology Ketorolac Tromethamine - therapeutic use Lymph - chemistry Lymph - cytology Lymph - drug effects Lymphatic Vessels - drug effects Male Rats Rats, Inbred Strains
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Zusammenfassung:	Single parenteral administration of ketorolac tromethamine produced a lymphotropic effect, which was manifested in acceleration of lymph flow in the thoracic duct and increase in contractile activity of the wall and valves in mesenteric lymphatic microvessels of rats with fever. These changes improved lymph circulation.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-005-0502-0