Comparative scintigraphic study of super(99m)Tc ciprofloxacin pharmacokinetics after intravenous and lymphotropic administration in experimental pulmonary suppuration

Intravenously injected super(99m)Tc ciprofloxacin is rapidly accumulated and washed from the septic focus. Lymphotropic injections provide targeted and long-lasting effect of the antibiotic. After injection into the interspinous ligament the drug slowly enters the inflammation area (by-passing the urinary organs and liver), where it is maximally accumulated only after 24 h, which allows to reduce the number of injections and the total dose of the antibiotic.