T1‐based sensing of mammographic density using single‐sided portable NMR

T1‐based sensing of mammographic density using single‐sided portable NMR

Purpose A single‐sided NMR instrument was used to investigate the ability of the T1 relaxation constant to distinguish between regions of low and high mammographic density in human breast tissue. Methods Measurements were performed on 5 breast slices obtained from 3 women undergoing breast reduction...

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Veröffentlicht in:Magnetic resonance in medicine 2018-09, Vol.80 (3), p.1243-1251
Hauptverfasser: Tourell, Monique C., Ali, Tonima S., Hugo, Honor J, Pyke, Chris, Yang, Samuel, Lloyd, Thomas, Thompson, Erik W., Momot, Konstantin I.
Format: Artikel
Sprache:eng
Schlagworte:
Breast
Breast cancer
breast cancer risk
Density
longitudinal spin‐relaxation time constant (T1)
mammographic density
Mammography
Mastectomy
Measurement methods
NMR
Nuclear magnetic resonance
portable single‐sided NMR
Statistical analysis
Surgery
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Zusammenfassung:Purpose A single‐sided NMR instrument was used to investigate the ability of the T1 relaxation constant to distinguish between regions of low and high mammographic density in human breast tissue. Methods Measurements were performed on 5 breast slices obtained from 3 women undergoing breast reduction surgery or prophylactic mastectomy. Results T1 values measured in regions of high mammographic density in both the full breast slices (T1 = 170 ± 30 ms) and excised regions (T1 = 160 ± 30 ms) were found to be significantly different (P 
ISSN:0740-3194
1522-2594
DOI:10.1002/mrm.27098