Complications and risk factors in pediatric bronchoscopy in a tertiary pediatric respiratory center

Bronchoscopy is an established procedure routinely used by pediatric pulmonologists. Despite its frequent application, data on complications and specific risk factors are scarce and sometimes conflicting. Aim The aim of this study was to evaluate frequency and severity of clearly defined complicatio...

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Veröffentlicht in:Pediatric pulmonology 2018-05, Vol.53 (5), p.619-627
Hauptverfasser: Carlens, Julia, Fuge, Jan, Price, Timothy, DeLuca, David S., Price, Mareike, Hansen, Gesine, Schwerk, Nicolaus
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Sprache:eng
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Zusammenfassung:Bronchoscopy is an established procedure routinely used by pediatric pulmonologists. Despite its frequent application, data on complications and specific risk factors are scarce and sometimes conflicting. Aim The aim of this study was to evaluate frequency and severity of clearly defined complications of bronchoscopy in children that occur both during and after the procedure, and to identify potential risk factors. Method A retrospective single‐center analysis of 670 elective bronchoscopies in 522 children aged 0‐17 years during the time period of 2008‐2012 was performed. Procedures in intensive care unit patients and children after lung transplantation were excluded. Results Mean patient age was 5.58 years, 61.5% had underlying chronic diseases. Intraprocedural complications occurred in 7.2% of all procedures; of these, hypoxemia was the most common, occuring in 4.8% of cases. Postprocedural adverse events were documented in 25.8%, the most frequent of which were fever in 14.2% and transient oxygen dependency in 13.4% of cases. No bronchoscopy related deaths occurred. Multivariate logistic regression was used to identify risk factors for (1) any complication, or (2) severe complications. Age below two years (OR 1.837 [1.224‐2.757], P = 0.003) and primary ciliary dyskinesia (OR 4.821 [2.018‐11.552], P 
ISSN:8755-6863
1099-0496
DOI:10.1002/ppul.23957