Leukocyte adhesion deficiency-I: A comprehensive review of all published cases

Leukocyte adhesion deficiency-I: A comprehensive review of all published cases

Deficiencies in CD18 prevent normal integrin dimerization and leukocyte adhesion to endothelial surfaces, processes essential to extravasation and antimicrobial activity.1,2 Severe LAD-I (predominantly classified as

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Bibliographische Detailangaben
Veröffentlicht in:The journal of allergy and clinical immunology in practice (Cambridge, MA) MA), 2018-07, Vol.6 (4), p.1418-1420.e10
Hauptverfasser: Almarza Novoa, Elena, Kasbekar, Sanchali, Thrasher, Adrian J., Kohn, Donald B., Sevilla, Julian, Nguyen, Tony, Schwartz, Jonathan D., Bueren, Juan A.
Format: Artikel
Sprache:eng
Schlagworte:
Age
Ear diseases
Infections
Medical prognosis
Mortality
Mutation
Neutrophils
Patients
Periodontics
Phenotypes
Pneumonia
Sepsis
Stem cells
Ulcers
Umbilical cord
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Beschreibung
Zusammenfassung:Deficiencies in CD18 prevent normal integrin dimerization and leukocyte adhesion to endothelial surfaces, processes essential to extravasation and antimicrobial activity.1,2 Severe LAD-I (predominantly classified as
ISSN:2213-2198
2213-2201
DOI:10.1016/j.jaip.2017.12.008