Cutis Laxa Acquisita After Urticarial Vasculitis in SLE Patients

Cutis laxa is a rare connective tissue disease involving damage to dermal elastic fibers creating a clinical appearance of loose, sagging skin. The condition can be either acquired or genetic. Autoimmune diseases, neoplasms, infections, and medications have been proposed as the cause of, or in assoc...

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Veröffentlicht in:The American journal of dermatopathology 2018-06, Vol.40 (6), p.433-437
Hauptverfasser: Golisch, Kimberly B, Gottesman, Silvija P, Ferrer, Patricia, Culpepper, Keliegh S
Format: Artikel
Sprache:eng
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Zusammenfassung:Cutis laxa is a rare connective tissue disease involving damage to dermal elastic fibers creating a clinical appearance of loose, sagging skin. The condition can be either acquired or genetic. Autoimmune diseases, neoplasms, infections, and medications have been proposed as the cause of, or in association with, the acquired form. In nearly 50% of cases, erythematous plaques present before the onset of cutis laxa. Separately, urticarial vasculitis and systemic lupus erythematosus have been linked to cutis laxa acquisita. Our case is the first in the literature documenting a coexistence of cutis laxa acquisita, hypocomplementemic urticarial vasculitis, and systemic lupus erythematosus.
ISSN:0193-1091
1533-0311
DOI:10.1097/DAD.0000000000001084