Effects of Direct Oral Anticoagulants at the Peak Phase, Trough Phase, and After Vascular Injury

Effects of Direct Oral Anticoagulants at the Peak Phase, Trough Phase, and After Vascular Injury

The mechanisms underlying the lower risk of hemorrhagic complications during treatment with direct oral anticoagulants (DOAC) have not been well clarified. Previous studies have evaluated the effects of DOAC on coagulation factors in the stationary state, but the effects of these agents after vascul...

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Veröffentlicht in:Journal of the American College of Cardiology 2018-01, Vol.71 (1), p.102-104
Hauptverfasser: Otuki, Sou, Izumi, Daisuke, Suda, Masayoshi, Sato, Akinori, Hasegawa, Yuki, Yagihara, Nobue, Iijima, Kenichi, Chinushi, Masaomi, Fuse, Ichiro, Minamino, Tohru
Format: Artikel
Sprache:eng
Schlagworte:
Anticoagulants
Cardiac arrhythmia
Cardiology
Catheters
Coagulation
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Zusammenfassung:The mechanisms underlying the lower risk of hemorrhagic complications during treatment with direct oral anticoagulants (DOAC) have not been well clarified. Previous studies have evaluated the effects of DOAC on coagulation factors in the stationary state, but the effects of these agents after vascular injury are unclear.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2017.10.076