Bevacuzimab May Be Less Effective in Obese Metastatic Colorectal Cancer Patients

Purpose The purpose of this study was to investigate whether obesity affects survival in metastatic colorectal cancer (mCRC) patients treated with bevacizumab combined with chemotherapy. Methods A total of 563 patients with mCRC who had received first-line chemotherapy in combination with bevacizuma...

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Veröffentlicht in:Journal of gastrointestinal cancer 2019-06, Vol.50 (2), p.214-220
Hauptverfasser: Artaç, Mehmet, Korkmaz, Levent, Coşkun, Hasan Şenol, Dane, Faysal, Karabulut, Bülent, Karaağaç, Mustafa, Çabuk, Devrim, Karabulut, Senem, Aykan, Nuri Faruk, Doruk, Hatice, Avcı, Nilüfer, Turhal, Nazım Serdar
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Sprache:eng
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Zusammenfassung:Purpose The purpose of this study was to investigate whether obesity affects survival in metastatic colorectal cancer (mCRC) patients treated with bevacizumab combined with chemotherapy. Methods A total of 563 patients with mCRC who had received first-line chemotherapy in combination with bevacizumab were studied. Patients were grouped as obese (BMI levels > 30) or non-obese (BMI levels
ISSN:1941-6628
1941-6636
DOI:10.1007/s12029-017-0047-2