Prognostic Value of Free Triiodothyronine Level in Patients With Hypertrophic Obstructive Cardiomyopathy

Prognostic Value of Free Triiodothyronine Level in Patients With Hypertrophic Obstructive Cardiomyopathy

Context Thyroid hormone acts as a fundamental regulator in cardiovascular homeostasis in pathophysiological conditions. Objective This study aims to determine whether thyroid hormone could be an independent predictor of adverse events in patients with hypertrophic obstructive cardiomyopathy (HOCM)....

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Veröffentlicht in:The journal of clinical endocrinology and metabolism 2018-03, Vol.103 (3), p.1198-1205
Hauptverfasser: Zhang, Kuo, Meng, Xiangbin, Wang, Wenyao, Zheng, Jilin, An, Shimin, Wang, Siyuan, Qi, Yu, Gao, Chuanyu, Tang, Yi-Da
Format: Artikel
Sprache:eng
Schlagworte:
Cardiomyopathy
Correlation analysis
Health risk assessment
Heart transplantation
Heart transplants
Homeostasis
Mortality
Risk factors
Thyroid gland
Thyroid hormones
Triiodothyronine
Ventricle
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Zusammenfassung:Context Thyroid hormone acts as a fundamental regulator in cardiovascular homeostasis in pathophysiological conditions. Objective This study aims to determine whether thyroid hormone could be an independent predictor of adverse events in patients with hypertrophic obstructive cardiomyopathy (HOCM). Design, Patients, and Outcome Measures The original cohort consisted of 965 consecutive patients with HOCM who were admitted to Fuwai Hospital from October 2009 to December 2014, and 756 patients completed thyroid function evaluations. Patients were divided into three groups according to free triiodothyronine (FT3) levels: tertile 1 (
ISSN:0021-972X
1945-7197
DOI:10.1210/jc.2017-02386