Assessment of the Embryonic Stem Cell Test and application and use in the pharmaceutical industry

BACKGROUND: The European Centre for the Validation of Alternative Methods (ECVAM) designed the Embryonic Stem Cell Test (EST) as a tool for classifying developmentally toxic compounds. An in vitro tool to assess developmental toxicity would be of great value to the pharmaceutical industry to help wi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Birth defects research. Part B. Developmental and reproductive toxicology 2008-04, Vol.83 (2), p.104-111
Hauptverfasser:	Paquette, Jennifer A., Kumpf, Steven W., Streck, Randal D., Thomson, Jason J., Chapin, Robert E., Stedman, Donald B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Testing Alternatives - methods Animals BALB 3T3 Cells Cell Differentiation - drug effects Cell Survival - drug effects Cells, Cultured developmentally toxic Drug Industry - methods Embryonic Stem Cell Test Embryonic Stem Cells - drug effects Embryonic Stem Cells - physiology embryotoxic EST Mice Mice, Inbred DBA pharmaceutical compounds Toxicity Tests - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!