Effectiveness of Low-Intensity Laser Therapy on Tissue Repair Following Saphenectomy in Patients Who Underwent Coronary Artery Bypass Graft: A Randomized, Double-Blind Study

Objective: To verify the effectiveness of low-intensity laser therapy (LLLT) on tissue repair following saphenectomy during postoperative period in patients having undergone coronary artery bypass graft (CABG). Materials and methods: A randomized clinical trial, controlled and double-blind study was conducted with 40 volunteers, divided into 2 groups: a placebo group (PG, n = 20) and a laser group (LG, n = 20). The patients in the LG group were irradiated with laser during saphenectomy (InGaAlP, λ 660 nm, energy density 6 J/cm 2 ) daily from the first to the fourth postoperative day. The surgical incision was clinically evaluated and imaged at the beginning and at the end of the treatment. The areas of hematoma and hyperemia were evaluated using the software ImageJ 1.4 © , and border closure was evaluated by three researchers, who were blinded concerning the allocation of the participants. Results: The LG group presented a reduction of the areas of hematoma and hyperemia ( p = 0.0003) and better border closure ( p = 0.009), when compared with the PG group. Conclusions: The proposed LLLT protocol improved the tissue repair following saphenectomy in CABG patients.