Osteogenic differentiation of mouse bone marrow stromal cells on fibroin microcarriers

We investigated the proliferation and osteogenic differentiation of mesenchymal stem cells cultured on fibroin microcarriers. Effective cell proliferation on the surface of the microcarriers, determined by the large surface area, and the contribution of microcarrier mineralization to the stimulation...

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Veröffentlicht in:	Doklady. Biochemistry and biophysics 2017-11, Vol.477 (1), p.345-348
Hauptverfasser:	Goncharenko, A. V., Kotlyarova, M. S., Moisenovich, A. M., Arkhipova, A. Y., Kulikov, D. A., Konkov, A. S., Kulikov, A. V., Mashkov, A. E., Agapov, I. I., Moisenovich, M. M., Kirpichnikov, M. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Bone marrow Bone Marrow Cells - cytology Cell Culture Techniques - methods Cell Differentiation Cell Proliferation Fibroins - chemistry Gelatin - chemistry Indoles - chemistry Life Sciences Mesenchymal Stem Cells - cytology Mesenchyme Mice Microspheres Mineralization Molecular Biology Osteogenesis Rodents Skin & tissue grafts Stem cell transplantation Stem cells Stromal cells
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Beschreibung
Zusammenfassung:	We investigated the proliferation and osteogenic differentiation of mesenchymal stem cells cultured on fibroin microcarriers. Effective cell proliferation on the surface of the microcarriers, determined by the large surface area, and the contribution of microcarrier mineralization to the stimulation of the osteogenic differentiation of mesenchymal stem cells was revealed.
ISSN:	1607-6729 1608-3091
DOI:	10.1134/S1607672917060011