‘Leukodystrophy‐like’ phenotype in children with myelin oligodendrocyte glycoprotein antibody‐associated disease

Aim To review the demographics and clinical and paraclinical parameters of children with myelin oligodendrocyte glycoprotein (MOG) antibody‐associated relapsing disease. Method In this UK‐based, multicentre study, 31 children with MOG antibody‐associated relapsing disease were studied retrospectivel...

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Veröffentlicht in:Developmental medicine and child neurology 2018-04, Vol.60 (4), p.417-423
Hauptverfasser: Hacohen, Yael, Rossor, Thomas, Mankad, Kshitij, Chong, Wk ‘Kling’, Lux, Andrew, Wassmer, Evangeline, Lim, Ming, Barkhof, Frederik, Ciccarelli, Olga, Hemingway, Cheryl
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Sprache:eng
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Zusammenfassung:Aim To review the demographics and clinical and paraclinical parameters of children with myelin oligodendrocyte glycoprotein (MOG) antibody‐associated relapsing disease. Method In this UK‐based, multicentre study, 31 children with MOG antibody‐associated relapsing disease were studied retrospectively. Results Of the 31 children studied, 14 presented with acute disseminated encephalomyelitis (ADEM); they were younger (mean 4.1y) than the remainder (mean 8.5y) who presented with optic neuritis and/or transverse myelitis (p
ISSN:0012-1622
1469-8749
DOI:10.1111/dmcn.13649