Identification of a KPC-9-producing Klebsiella pneumoniae ST258 cluster among KPC-2-producing isolates of an ongoing outbreak in Northwestern Greece: a retrospective study

Identification of a KPC-9-producing Klebsiella pneumoniae ST258 cluster among KPC-2-producing isolates of an ongoing outbreak in Northwestern Greece: a retrospective study

We identified the first nosocomial outbreak of KPC-9-producing isolates. Genetic comparison between our isolates and isolates of KPC-KP ST258 associated with Greece indicated that blaKPC-9 may have been replaced by blaKPC-2 on the pKpQiL- plasmid in KPC-KP ST258. The KPC-9-KP outbreak cluster is clo...

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Veröffentlicht in:Clinical microbiology and infection 2018-05, Vol.24 (5), p.558-560
Hauptverfasser: Gartzonika, K., Rossen, J.W.A., Sakkas, H., Rosema, S., Priavali, E., Friedrich, A.W., Levidiotou, S., Bathoorn, E.
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Sprache:eng
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Zusammenfassung:We identified the first nosocomial outbreak of KPC-9-producing isolates. Genetic comparison between our isolates and isolates of KPC-KP ST258 associated with Greece indicated that blaKPC-9 may have been replaced by blaKPC-2 on the pKpQiL- plasmid in KPC-KP ST258. The KPC-9-KP outbreak cluster is closely related to the KPC-2-KP outbreak in Greece. Screening for specific sublineages of KPC-KP ST258 by molecular tests may become an important tool in outbreak investigation.
ISSN:1198-743X
1469-0691
DOI:10.1016/j.cmi.2017.12.007