Does nurse job satisfaction influence adherence to the central line insertion checklist and central line–associated bloodstream infections in the Veterans Health Administration?

•We conducted an analysis using 4 years of data from intensive care nurses in Veterans Health Administration hospitals.•Rates of global job satisfaction were assessed for a relationship with reported adherence to the central line insertion checklist and central line–associated bloodstream infections.•Higher job satisfaction was related to a decreased relative risk of central line–associated bloodstream infections, but not an increase in reported checklist adherence. Nurses satisfied with their jobs report less job stress, more effective nurse-physician collaboration, and higher patient satisfaction scores. It is unknown if job satisfaction influences adherence to best practices or patient outcomes. This secondary data analysis investigated the relationship between job satisfaction, adherence to the central line insertion checklist, and central line–associated bloodstream infections (CLABSIs). Results showed a decreased risk of CLABSI with higher job satisfaction, on average. No relationship was observed with checklist adherence.