Decline of rotavirus-coded hospitalizations in children under 5 years: A report from Japan where rotavirus vaccines are self-financed

Decline of rotavirus-coded hospitalizations in children under 5 years: A report from Japan where rotavirus vaccines are self-financed

•The largest-scale study assessed the impact of rotavirus vaccines in Japan.•Rotavirus vaccines have been moderately covered without routine immunization.•Rotavirus-coded hospitalization declined by 60–70% from 2009 to 2015.•Results suggest indirect effect in older children least likely to be vaccin...

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Veröffentlicht in:Vaccine 2018-05, Vol.36 (19), p.2727-2732
Hauptverfasser: Kobayashi, Masayuki, Adachi, Noriaki, Miyazaki, Makoto, Tatsumi, Masatoshi
Format: Artikel
Sprache:eng
Schlagworte:
Age
Child, Preschool
Children
Data processing
Gastroenteritis
Health insurance
Hospitalization
Hospitalization - statistics & numerical data
Humans
Immunization
Incidence
Infant
Insurance claims
Japan - epidemiology
Observational studies
Reduction
Retrospective Studies
Rotavirus
Rotavirus gastroenteritis
Rotavirus Infections - epidemiology
Rotavirus Infections - prevention & control
Rotavirus Vaccines - economics
Rotavirus Vaccines - therapeutic use
Seasons
Vaccine
Vaccines
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Beschreibung
Zusammenfassung:•The largest-scale study assessed the impact of rotavirus vaccines in Japan.•Rotavirus vaccines have been moderately covered without routine immunization.•Rotavirus-coded hospitalization declined by 60–70% from 2009 to 2015.•Results suggest indirect effect in older children least likely to be vaccinated. To estimate the trend in incidence of rotavirus gastroenteritis (RVGE) hospitalization among children aged
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2017.10.033