Multilocus Genotyping of Cryptosporidium sp. Isolates from Human Immunodeficiency Virus-Infected Individuals in South India

This study characterized cryptosporidial infections in 48 human immunodeficiency virus-infected individuals in India by multilocus genotyping. Cryptosporidium hominis, C. parvum, C. felis, C. muris, and C. meleagridis were identified. Cpgp40/15 PCR-restriction fragment length polymorphism identified...

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Veröffentlicht in:	Journal of Clinical Microbiology 2006-02, Vol.44 (2), p.632-634
Hauptverfasser:	Muthusamy, Dheepa, Rao, Sitara S, Ramani, Sasirekha, Monica, Bindhu, Banerjee, Indrani, Abraham, Ooriapadickal C, Mathai, Dilip C, Primrose, Beryl, Muliyil, Jayaprakash, Wanke, Christine A, Ward, Honorine D, Kang, Gagandeep
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS-Related Opportunistic Infections - parasitology Animals Biological and medical sciences Cryptosporidiosis - parasitology Cryptosporidium Cryptosporidium - classification Cryptosporidium - genetics Cryptosporidium - isolation & purification Cryptosporidium felis Cryptosporidium hominis Cryptosporidium meleagridis Cryptosporidium muris Cryptosporidium parvum DNA, Protozoan - analysis Felis Fundamental and applied biological sciences. Psychology Genotype HIV Infections - complications Human immunodeficiency virus Human viral diseases Humans India Infectious diseases Medical sciences Microbiology Molecular Sequence Data Parasitology Polymerase Chain Reaction Polymorphism, Restriction Fragment Length Protozoan Proteins - genetics Sequence Analysis, DNA Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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Zusammenfassung:	This study characterized cryptosporidial infections in 48 human immunodeficiency virus-infected individuals in India by multilocus genotyping. Cryptosporidium hominis, C. parvum, C. felis, C. muris, and C. meleagridis were identified. Cpgp40/15 PCR-restriction fragment length polymorphism identified six subgenotypes. Cryptosporidial diarrhea was associated with decreased CD4 counts, below 200 (P = 0.009), but not high viral loads.
ISSN:	0095-1137 1098-660X 1098-5530
DOI:	10.1128/JCM.44.2.632-634.2006