Association of estimated glomerular filtration rate with muscle function in older persons who have fallen

Abstract Background studies suggest that estimated glomerular filtration rate (eGFR) is less reliable in older persons and that a low serum-creatinine might reflect reduced muscle mass rather than high kidney function. This study investigates the possible relationship between eGFR and multiple eleme...

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Veröffentlicht in:Age and ageing 2018-03, Vol.47 (2), p.269-274
Hauptverfasser: Tap, Lisanne, Boyé, Nicole D A, Hartholt, Klaas A, van der Cammen, Tischa J M, Mattace-Raso, Francesco U S
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Sprache:eng
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Zusammenfassung:Abstract Background studies suggest that estimated glomerular filtration rate (eGFR) is less reliable in older persons and that a low serum-creatinine might reflect reduced muscle mass rather than high kidney function. This study investigates the possible relationship between eGFR and multiple elements of physical performance in older fallers. Methods baseline data of the IMPROveFALL-study were examined in participants ≥65 years. Serum-creatinine based eGFR was classified as normal (≥90 ml/min), mildly reduced (60–89 ml/min) or moderately–severely reduced (
ISSN:0002-0729
1468-2834
DOI:10.1093/ageing/afx180