Intermittent Reprogramming: A Breath of Fresh Air for Lung Regeneration

Intermittent Reprogramming: A Breath of Fresh Air for Lung Regeneration

Recently in Stem Cell Reports, Guo et al. (2017) adopted an intermittent reprogramming strategy to generate “induced Progenitor-Like (iPL)” cells, which can maintain lineage commitment while undergoing controlled expansion. The iPLCs were successfully engrafted into a damaged airway, highlighting th...

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Veröffentlicht in:Cell stem cell 2017-12, Vol.21 (6), p.712-714
1. Verfasser: Firth, Amy L.
Format: Artikel
Sprache:eng
Schlagworte:
Cellular Reprogramming
Epithelial Cells
Regeneration
Regenerative Medicine
Stem Cells
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Zusammenfassung:Recently in Stem Cell Reports, Guo et al. (2017) adopted an intermittent reprogramming strategy to generate “induced Progenitor-Like (iPL)” cells, which can maintain lineage commitment while undergoing controlled expansion. The iPLCs were successfully engrafted into a damaged airway, highlighting this significant advancement for regenerative medicine strategies in the lung. Recently in Stem Cell Reports, Guo et al. (2017) adopted an intermittent reprogramming strategy to generate “induced Progenitor-Like (iPL)” cells, which can maintain lineage commitment while undergoing controlled expansion. The iPLCs were successfully engrafted into a damaged airway, highlighting this significant advancement for regenerative medicine strategies in the lung.
ISSN:1934-5909
1875-9777
DOI:10.1016/j.stem.2017.11.015