A novel ultradeformable liposomes of Naringin for anti-inflammatory therapy

A novel ultradeformable liposomes of Naringin for anti-inflammatory therapy

[Display omitted] •Nanovesicles were small in size and monodispersed independently of the NA concentration.•No citotoxity effects were observed in 3T3 fibroblasts treated with ultradeformable liposomes.•Ultradeformable liposomes have the ability to reduce skin inflammation. Ultradeformable liposomes...

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Veröffentlicht in:Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2018-02, Vol.162, p.265-270
Hauptverfasser: Pleguezuelos-Villa, María, Mir-Palomo, Silvia, Díez-Sales, Octavio, Buso, M.A. Ofelia Vila, Sauri, Amparo Ruiz, Nácher, Amparo
Format: Artikel
Sprache:eng
Schlagworte:
Anti-inflammatory
Fibroblasts
In vivo studies
Naringin
Transdermal penetration
Ultradeformable liposomes
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Zusammenfassung:[Display omitted] •Nanovesicles were small in size and monodispersed independently of the NA concentration.•No citotoxity effects were observed in 3T3 fibroblasts treated with ultradeformable liposomes.•Ultradeformable liposomes have the ability to reduce skin inflammation. Ultradeformable liposomes were formulated using naringin (NA), a flavanone glycoside, at different concentrations (3, 6 and 9mg/mL). Nanovesicles were small size (∼100nm), regardless of the NA concentration used, and monodisperse (PI
ISSN:0927-7765
1873-4367
DOI:10.1016/j.colsurfb.2017.11.068