Post-chikungunya chronic inflammatory rheumatism: Follow-up of cases after 1 year of infection in Tolima, Colombia

Chronic Inflammatory Rheumatism (CIR) is one of the recognized and increasingly reported consequence post-chikungunya infection (pCHIK) in Colombia and Latin America. Retrospective cohort study of 128 patients with CHIK that persisted with pCHIK-CIR after 59–68 weeks (1.13–1.31 years). This informat...

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Veröffentlicht in:Travel medicine and infectious disease 2018-01, Vol.21, p.62-68
Hauptverfasser: Consuegra-Rodríguez, Mónika Patricia, Hidalgo-Zambrano, Diana Meliza, Vásquez-Serna, Heriberto, Jimenez-Canizales, Carlos E., Parra-Valencia, Esteban, Rodriguez-Morales, Alfonso J.
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Sprache:eng
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Zusammenfassung:Chronic Inflammatory Rheumatism (CIR) is one of the recognized and increasingly reported consequence post-chikungunya infection (pCHIK) in Colombia and Latin America. Retrospective cohort study of 128 patients with CHIK that persisted with pCHIK-CIR after 59–68 weeks (1.13–1.31 years). This information was evaluated by means of a telephone survey and according to validated criteria (WHO 2015) previously (patients with >12 weeks post-CHIK with ≥1 manifestations [continuous/recurrent]: chronic polyarthralgia [pCHIK-CPA], stiffness and/or joint edema). Of the total CHIK-infected subjects finally included (n = 65), 28 (43.1%) reported pCHIK-CPA; and 38 patients (58.5%) at least one persistent rheumatological symptoms over the last year (pCHIK-CIR); 38.5% of them, morning stiffness, 18.5% joint edema, and 3.1% joint redness. No significant sex differences were found; 60% of patients with pCHIK-CPA aged> 40 years (RR = 3.75; 95%CI 1.47–9.53). The 29.2% of patients required medical attention because of symptoms. Nearly half of patients with CHIK had at least one rheumatologic symptom persistent over a year, and the third of them, pCHIK-CPA. These results are comparable with previous estimates obtained in other cohorts in the country (Risaralda and Sucre) and are consistent with results from other studies in France and India.
ISSN:1477-8939
1873-0442
DOI:10.1016/j.tmaid.2017.11.013