Prognostic Factors for Survival After Transarterial Chemoembolization Combined with Sorafenib in the Treatment of BCLC Stage B and C Hepatocellular Carcinomas

The objective of this study was to analyze prognostic factors for survival after transarterial chemoembolization (TACE) combined with sorafenib for hepatocellular carcinoma (HCC) of Barcelona Clinic Liver Cancer (BCLC) stages B and C. Clinical data of 198 patients with BCLC stage B and C HCCs who un...

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Veröffentlicht in:Academic radiology 2018-04, Vol.25 (4), p.423-429
Hauptverfasser: Ni, Jia-yan, Kong, Jian, Sun, Hong-liang, Chen, Yao-ting, Luo, Jiang-hong, Wang, Wei-dong, Chen, Dong, Jiang, Xiong-ying, Xu, Lin-feng
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Sprache:eng
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Zusammenfassung:The objective of this study was to analyze prognostic factors for survival after transarterial chemoembolization (TACE) combined with sorafenib for hepatocellular carcinoma (HCC) of Barcelona Clinic Liver Cancer (BCLC) stages B and C. Clinical data of 198 patients with BCLC stage B and C HCCs who underwent TACE combined with sorafenib between June 2012 and January 2017 were retrospectively collected and analyzed. Survival curves were detected using log-rank test. Univariate analysis was performed using log-rank test with respect to 11 prognostic factors potentially affecting survival. All statistically significant prognostic factors identified by univariate analysis were entered into a Cox proportion hazards regression model to identify independent predictors of survival. P values were two-sided and P 
ISSN:1076-6332
1878-4046
DOI:10.1016/j.acra.2017.10.018