Programming Recognition Arrays through Double Chalcogen‐Bonding Interactions

In this work, we have programmed and synthesized a recognition motif constructed around a chalcogenazolo‐pyridine scaffold (CGP) that, through the formation of frontal double chalcogen‐bonding interactions, associates into dimeric EX‐type complexes. The reliability of the double chalcogen‐bonding interaction has been shown at the solid‐state by X‐ray analysis, depicting the strongest recognition persistence for a Te‐congener. The high recognition fidelity, chemical and thermal stability and easy derivatization at the 2‐position makes CGP a convenient motif for constructing supramolecular architectures through programmed chalcogen‐bonding interactions. A recognition motif constructed around a chalcogenazolo‐pyridine scaffold (CGP) has been programmed and synthesized that, through the formation of frontal double chalcogen‐bonding interactions, associates into dimeric EX‐type complexes. The reliability of the double chalcogen‐bonding interaction has been shown at the solid‐state by X‐ray analysis, depicting the strongest recognition persistence for a Te‐congener.