Effect of Xylan Sulfates on Coagulation of Human Blood Plasma

Sulfated derivatives of xylan (isolated from Bétula pubéscens wood) with average molecular weight ~34 kDa, sulfur content of 11.3-17.5%, a degree of substitution of 0.74-1.64 are anticoagulants of direct type of action. Antithrombin and antifactor Xa activities in three tested xylan samples did not...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2017-12, Vol.164 (2), p.158-161
Hauptverfasser: Drozd, N. N., Kuznetsova, S. A., Levdansky, V. A., Mikhailenko, M. A.
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Sprache:eng
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Zusammenfassung:Sulfated derivatives of xylan (isolated from Bétula pubéscens wood) with average molecular weight ~34 kDa, sulfur content of 11.3-17.5%, a degree of substitution of 0.74-1.64 are anticoagulants of direct type of action. Antithrombin and antifactor Xa activities in three tested xylan samples did not differ and reached 30.8-31.8 and 13.5-14.3 U/mg, respectively.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-017-3947-z