Prospect of Using Cell Product for the Therapy of Skin Defects in Diabetes Mellitus
The effectiveness of autologous cell product in the therapy of skin burn wounds was studied in C57B1/6 male mice against the background of streptozotocin-induced diabetes mellitus. In animals with and without modeled diabetes mellitus, significant decrease in skin defect area was observed after sing...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 2017-12, Vol.164 (2), p.266-268 |
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| container_title | Bulletin of experimental biology and medicine |
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| creator | Lykov, A. P. Bondarenko, N. A. Poveshchenko, O. V. Miller, T. V. Poveshchenko, A. F. Surovtseva, M. A. Bgatova, N. P. Konenkov, V. I. |
| description | The effectiveness of autologous cell product in the therapy of skin burn wounds was studied in C57B1/6 male mice against the background of streptozotocin-induced diabetes mellitus. In animals with and without modeled diabetes mellitus, significant decrease in skin defect area was observed after single administration of the cell product (bone marrow multipotent mesenchymal stromal cells, fibroblasts or media conditioned by these cells). |
| doi_str_mv | 10.1007/s10517-017-3970-0 |
| format | Article |
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P. ; Bondarenko, N. A. ; Poveshchenko, O. V. ; Miller, T. V. ; Poveshchenko, A. F. ; Surovtseva, M. A. ; Bgatova, N. P. ; Konenkov, V. I.</creator><creatorcontrib>Lykov, A. P. ; Bondarenko, N. A. ; Poveshchenko, O. V. ; Miller, T. V. ; Poveshchenko, A. F. ; Surovtseva, M. A. ; Bgatova, N. P. ; Konenkov, V. I.</creatorcontrib><description>The effectiveness of autologous cell product in the therapy of skin burn wounds was studied in C57B1/6 male mice against the background of streptozotocin-induced diabetes mellitus. In animals with and without modeled diabetes mellitus, significant decrease in skin defect area was observed after single administration of the cell product (bone marrow multipotent mesenchymal stromal cells, fibroblasts or media conditioned by these cells).</description><identifier>ISSN: 0007-4888</identifier><identifier>EISSN: 1573-8221</identifier><identifier>DOI: 10.1007/s10517-017-3970-0</identifier><identifier>PMID: 29178052</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Autografts ; Biomedical and Life Sciences ; Biomedicine ; Bone marrow ; Cell Biology ; Dermatologic agents ; Diabetes ; Diabetes mellitus ; Diabetes therapy ; Diabetic foot ; Fibroblasts ; Internal Medicine ; Laboratory Medicine ; Mesenchymal stem cells ; Mesenchyme ; Neovascularization ; Pathology ; Rodents ; Skin ; Skin care ; Stem cells ; Streptozocin ; Stromal cells ; Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine) ; Wounds</subject><ispartof>Bulletin of experimental biology and medicine, 2017-12, Vol.164 (2), p.266-268</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2017</rights><rights>COPYRIGHT 2017 Springer</rights><rights>Bulletin of Experimental Biology and Medicine is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-57f8199271b49fc5a3595e57559c90b4593dd3d6ac1b6fa4205555bccf96ebbb3</citedby><cites>FETCH-LOGICAL-c470t-57f8199271b49fc5a3595e57559c90b4593dd3d6ac1b6fa4205555bccf96ebbb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10517-017-3970-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10517-017-3970-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29178052$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lykov, A. P.</creatorcontrib><creatorcontrib>Bondarenko, N. A.</creatorcontrib><creatorcontrib>Poveshchenko, O. V.</creatorcontrib><creatorcontrib>Miller, T. V.</creatorcontrib><creatorcontrib>Poveshchenko, A. F.</creatorcontrib><creatorcontrib>Surovtseva, M. A.</creatorcontrib><creatorcontrib>Bgatova, N. P.</creatorcontrib><creatorcontrib>Konenkov, V. I.</creatorcontrib><title>Prospect of Using Cell Product for the Therapy of Skin Defects in Diabetes Mellitus</title><title>Bulletin of experimental biology and medicine</title><addtitle>Bull Exp Biol Med</addtitle><addtitle>Bull Exp Biol Med</addtitle><description>The effectiveness of autologous cell product in the therapy of skin burn wounds was studied in C57B1/6 male mice against the background of streptozotocin-induced diabetes mellitus. In animals with and without modeled diabetes mellitus, significant decrease in skin defect area was observed after single administration of the cell product (bone marrow multipotent mesenchymal stromal cells, fibroblasts or media conditioned by these cells).</description><subject>Autografts</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Bone marrow</subject><subject>Cell Biology</subject><subject>Dermatologic agents</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes therapy</subject><subject>Diabetic foot</subject><subject>Fibroblasts</subject><subject>Internal Medicine</subject><subject>Laboratory Medicine</subject><subject>Mesenchymal stem cells</subject><subject>Mesenchyme</subject><subject>Neovascularization</subject><subject>Pathology</subject><subject>Rodents</subject><subject>Skin</subject><subject>Skin care</subject><subject>Stem cells</subject><subject>Streptozocin</subject><subject>Stromal cells</subject><subject>Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)</subject><subject>Wounds</subject><issn>0007-4888</issn><issn>1573-8221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp1kV9vFCEUxYnR2G31A_hiSExMX6bCzDDAY7P1X1KjSdtnAsxllzo7rDDz0G_vnWzV1iiEAJffObnkEPKKszPOmHxXOBNcVgxXoyWr2BOy4kI2lapr_pSsGEJVq5Q6Isel3C5X1vHn5KjWXCom6hW5-pZT2YOfaAr0psRxQ9cwDBTL_YzVkDKdtkCvt5Dt_m6hrr7HkV5AQFGhyzFaBxMU-gWFcZrLC_Is2KHAy_v9hNx8eH-9_lRdfv34eX1-WflWsqkSMiiudS25a3XwwjZCCxBSCO01c63QTd83fWc9d12wbc0EDud90B0455oTcnrw3ef0Y4YymV0sHpuwI6S5GK47rRu0k4i--Qu9TXMesbuFUlwxJbo_1MYOYOIY0pStX0zNuagFV61sOFJn_6Bw9rCLPo0QItYfCd4-EGzBDtO2pGGeYhrLY5AfQI-hlAzB7HPc2XxnODNL4uaQuMHEzZK4Yah5ff-z2e2g_634FTEC9QEo-DRuID_4-n9dfwISB7HG</recordid><startdate>20171201</startdate><enddate>20171201</enddate><creator>Lykov, A. 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A. ; Poveshchenko, O. V. ; Miller, T. V. ; Poveshchenko, A. F. ; Surovtseva, M. A. ; Bgatova, N. P. ; Konenkov, V. I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-57f8199271b49fc5a3595e57559c90b4593dd3d6ac1b6fa4205555bccf96ebbb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Autografts</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Bone marrow</topic><topic>Cell Biology</topic><topic>Dermatologic agents</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetes therapy</topic><topic>Diabetic foot</topic><topic>Fibroblasts</topic><topic>Internal Medicine</topic><topic>Laboratory Medicine</topic><topic>Mesenchymal stem cells</topic><topic>Mesenchyme</topic><topic>Neovascularization</topic><topic>Pathology</topic><topic>Rodents</topic><topic>Skin</topic><topic>Skin care</topic><topic>Stem cells</topic><topic>Streptozocin</topic><topic>Stromal cells</topic><topic>Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)</topic><topic>Wounds</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lykov, A. 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In animals with and without modeled diabetes mellitus, significant decrease in skin defect area was observed after single administration of the cell product (bone marrow multipotent mesenchymal stromal cells, fibroblasts or media conditioned by these cells).</abstract><cop>New York</cop><pub>Springer US</pub><pmid>29178052</pmid><doi>10.1007/s10517-017-3970-0</doi><tpages>3</tpages></addata></record> |
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| ispartof | Bulletin of experimental biology and medicine, 2017-12, Vol.164 (2), p.266-268 |
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| subjects | Autografts Biomedical and Life Sciences Biomedicine Bone marrow Cell Biology Dermatologic agents Diabetes Diabetes mellitus Diabetes therapy Diabetic foot Fibroblasts Internal Medicine Laboratory Medicine Mesenchymal stem cells Mesenchyme Neovascularization Pathology Rodents Skin Skin care Stem cells Streptozocin Stromal cells Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine) Wounds |
| title | Prospect of Using Cell Product for the Therapy of Skin Defects in Diabetes Mellitus |
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