A novel immunosuppressive pathway involving peroxynitrate-mediated nitration of platelet antigens within antigen-presenting cells
BACKGROUND: Studies have demonstrated that immunity against platelet (PLT) transfusions is dependent on recipient antigen‐presenting cells (APCs) and their ability to produce nitric oxide (NO). To further analyze this, we focused on NO's major metabolite peroxynitrite (ONOO‐) and its ability to...
Gespeichert in:
Veröffentlicht in: | Transfusion (Philadelphia, Pa.) Pa.), 2008-09, Vol.48 (9), p.1917-1924 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Schreiben Sie den ersten Kommentar!