Short body length phenotype is compensated by the upregulation of nidogen family members in a deleterious nid1a mutation of zebrafish
To decode biological processes,interfering with gene functions is a widely used strategy.There are a number of ways to interfere with gene functions.For instance,small interfering RNAs(siRNAs)are used to induce mRNA degradation;morpholinos are used to block protein translation(Nasevicius and Ekker,2...
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Veröffentlicht in: | Journal of genetics and genomics 2017-11, Vol.44 (11), p.553-556 |
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container_title | Journal of genetics and genomics |
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creator | Zhu, Peipei Ma, Zhipeng Guo, Liwei Zhang, Wei Zhang, Qinghe Zhao, Ting Jiang, Kunpeng Peng, Jinrong Chen, Jun |
description | To decode biological processes,interfering with gene functions is a widely used strategy.There are a number of ways to interfere with gene functions.For instance,small interfering RNAs(siRNAs)are used to induce mRNA degradation;morpholinos are used to block protein translation(Nasevicius and Ekker,2000); |
doi_str_mv | 10.1016/j.jgg.2017.09.011 |
format | Article |
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source | MEDLINE; Elsevier ScienceDirect Journals Complete; Alma/SFX Local Collection |
subjects | Animals Body Size - genetics Calcium-Binding Proteins - deficiency Calcium-Binding Proteins - genetics Membrane Glycoproteins - deficiency Membrane Glycoproteins - genetics Phenotype Sequence Deletion Up-Regulation Zebrafish - anatomy & histology Zebrafish - genetics Zebrafish Proteins - deficiency Zebrafish Proteins - genetics |
title | Short body length phenotype is compensated by the upregulation of nidogen family members in a deleterious nid1a mutation of zebrafish |
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