Short body length phenotype is compensated by the upregulation of nidogen family members in a deleterious nid1a mutation of zebrafish

To decode biological processes,interfering with gene functions is a widely used strategy.There are a number of ways to interfere with gene functions.For instance,small interfering RNAs（siRNAs）are used to induce mRNA degradation;morpholinos are used to block protein translation（Nasevicius and Ekker,2000）;