Ciliatamides A-C, Bioactive Lipopeptides from the Deep-Sea Sponge Aaptos ciliata super(#)

Ciliatamides A-C, Bioactive Lipopeptides from the Deep-Sea Sponge Aaptos ciliata super(#)

Three lipopeptides, ciliatamides A-C (1-3), were isolated from the deep- sea sponge Aaptos ciliata, and their structures were elucidated on the basis of spectroscopic and chemical methods. Ciliatamides A (1) and B (2) were found to be antileishmanial, while 2 also exhibited marginal cytotoxicity to...

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2008-01, Vol.71 (3), p.469-472
Hauptverfasser: Fusetani, Nobuhiro, Nakao, Yoichi, van Soest, RobWM, Kawatsu, Shizuka, Matsunaga, Shigeki, Okamoto, Masaaki, Okamoto, Chikane, Matsumoto, Yoshitsugu
Format: Artikel
Sprache:eng
Schlagworte:
Aaptos
Ciliata
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Zusammenfassung:Three lipopeptides, ciliatamides A-C (1-3), were isolated from the deep- sea sponge Aaptos ciliata, and their structures were elucidated on the basis of spectroscopic and chemical methods. Ciliatamides A (1) and B (2) were found to be antileishmanial, while 2 also exhibited marginal cytotoxicity to HeLa cells.
ISSN:0163-3864
1520-6025
DOI:10.1021/np8000317