Novel Arylhydrazone-Conjugated Gold Nanoparticles with DNA-Cleaving Ability: The First DNA-Nicking Nanomaterial

Arylhydrazones were linked onto gold nanoparticles through the poly(ethylene glycol) spacer to produce a new type of photoinduced DNA-cleaving nanomaterials with great potency.

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Bibliographische Detailangaben
Veröffentlicht in:	Bioconjugate chemistry 2007-11, Vol.18 (6), p.1709-1712
Hauptverfasser:	Hsu, Ming-Hua, Josephrajan, Thainashmuthu, Yeh, Chen-Sheng, Shieh, Dar-Bin, Su, Wu-Chou, Hwu, Jih Ru
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA - chemistry DNA - metabolism DNA Breaks, Single-Stranded Gold - chemistry Hydrazines - chemistry Microscopy, Electron, Transmission Molecular Structure Nanoparticles - chemistry Nanoparticles - ultrastructure
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Arylhydrazones were linked onto gold nanoparticles through the poly(ethylene glycol) spacer to produce a new type of photoinduced DNA-cleaving nanomaterials with great potency.
ISSN:	1043-1802 1520-4812
DOI:	10.1021/bc700222n