Complications and monitoring of percutaneous renal biopsy - a retrospective study

Percutaneous renal biopsy is a necessary tool to diagnose renal diseases but complications may still occur. The aims of this study were to detect the rate of complications, possible risk factors and to identify the necessity of routine post-biopsy controls at 4 - 6, and 24 hours. This single-center retrospective study included 500 consecutive biopsies of native and allograft kidneys performed at the Jena University Hospital. Major complications occurred in 2.4% of all cases: 9 patients received blood transfusions (1.8%), 2 arterial-venous fistulas (0.4%), 1 angiographic intervention (0.2%), no surgical intervention or death. Minor complications after 24 (4 - 6) hours appeared in 31.8 (41.2)%: 14.8 (11.0)% had hematomas detected by ultrasound (n = 74), 17.0 (30.2)% a reduction of hemoglobin concentration ≥ 1.0 g/dL (n = 85), 4.8 (2.6)% both (n = 24), 1 macrohematuria (0.2%). Systolic blood pressure (≥ 155 mmHg vs. ≤ 126 mmHg, OR 2.007, 95% CI 1.003 - 4.018, p = 0.049) and younger age (per 1 year increase, OR 0.983, 95% CI 0.968 - 0.998, p = 0.027) were associated with the presence of hematoma. Baseline hemoglobin (per increase of 1.6 g/dL, OR 1.499, 95% CI 1.222 - 1.840, p