Addressing the post-irradiation hypothalamic-pituitary endocrine abnormalities of brain tumors in pediatric patients

Addressing the post-irradiation hypothalamic-pituitary endocrine abnormalities of brain tumors in pediatric patients

Hypothalamic-pituitary axis is susceptible to radiotherapy, causing endocrine disorders to childhood cancer survivors. We conducted a systematic review in order to assess the radiation-induced toxicity that leads to hormone secretion abnormalities and their severity in children with brain tumors. Th...

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Veröffentlicht in:Journal of B.U. ON. 2017-09, Vol.22 (5), p.1240-1245
Hauptverfasser: Velentza, Louloudenia, Tolia, Maria, Christakou, Charikleia, Nikolaou, Michail, Zerdes, Ioannis, Tsoukalas, Nikolaos, Hajiioannou, Jiannis, Tsanadis, Konstantinos, Rigas, Georgios, Mitsis, Michail, Theodorou, Kyriaki, Pistevou-Gombaki, Kyriaki, Tsekeris, Periklis, Kyrgias, George
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Sprache:eng
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Zusammenfassung:Hypothalamic-pituitary axis is susceptible to radiotherapy, causing endocrine disorders to childhood cancer survivors. We conducted a systematic review in order to assess the radiation-induced toxicity that leads to hormone secretion abnormalities and their severity in children with brain tumors. The data were collected by relevant studies on PubMed and EMBASE. Articles up to December 2016 were included. We selected studies which focused on children patients (
ISSN:1107-0625