Does renal function affect the efficacy or safety of a pharmacoinvasive strategy in patients with ST-elevation myocardial infarction? A meta-analysis

Does renal function affect the efficacy or safety of a pharmacoinvasive strategy in patients with ST-elevation myocardial infarction? A meta-analysis

The efficacy and safety of pharmacoinvasive strategy following fibrinolysis for ST-elevation myocardial infarction (STEMI) in relation to renal function have not been established. Using patient-level data from 4 randomized controlled trials, we examined the efficacy and safety of pharmacoinvasive ve...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The American heart journal 2017-11, Vol.193, p.46-54
Hauptverfasser: Russo, Juan J., Goodman, Shaun G., Cantor, Warren J., Ko, Dennis T., Bagai, Akshay, Tan, Mary K., Di Mario, Carlo, Halvorsen, Sigrun, Le May, Michel, Fernandez-Avilés, Francisco, Scheller, Bruno, Armstrong, Paul W., Borgia, Francesco, Piscione, Federico, Sanchez, Pedro L., Yan, Andrew T.
Format: Artikel
Sprache:eng
Schlagworte:
Acute coronary syndromes
Angioplasty
Bleeding
Cardiovascular disease
Clinical outcomes
Clinical trials
Effectiveness
Electrocardiography
Epidermal growth factor receptors
Fibrinolysis
Fibrinolytic Agents - therapeutic use
Glomerular filtration rate
Glomerular Filtration Rate - drug effects
Heart attacks
Hemodialysis
Humans
Impairment
Intervention
Kidney - drug effects
Kidney - physiopathology
Kidney diseases
Medical imaging
Meta-analysis
Mortality
Myocardial infarction
Patients
Pharmacology
Practice Guidelines as Topic
Renal function
Safety
ST Elevation Myocardial Infarction - drug therapy
ST Elevation Myocardial Infarction - physiopathology
Strategy
Stratigraphy
Thrombolysis
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The efficacy and safety of pharmacoinvasive strategy following fibrinolysis for ST-elevation myocardial infarction (STEMI) in relation to renal function have not been established. Using patient-level data from 4 randomized controlled trials, we examined the efficacy and safety of pharmacoinvasive versus standard treatment after fibrinolysis for STEMI. Patients were stratified based on the estimated glomerular filtration rate (eGFR) on presentation (
ISSN:0002-8703
1097-6744
DOI:10.1016/j.ahj.2017.07.015