Frequency and Significance of Intravascular Hemolysis Before and After Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis

Intravascular hemolysis (IVH) has been identified in patients with surgical prosthetic valves, but few have been reported after transcatheter aortic valve implantation (TAVI). We conducted a prospective analysis of 64 TAVI patients. The hemolysis profiles were collected at baseline and 6 months afte...

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Veröffentlicht in:	The American journal of cardiology 2018-01, Vol.121 (1), p.69-72
Hauptverfasser:	Ko, Tsung-Yu, Lin, Mao-Shin, Lin, Lung-Chun, Liu, Ying-Ju, Yeh, Chih-Fan, Huang, Ching-Chang, Chen, Ying-Hsien, Chen, Yih-Sharng, Kao, Hsien-Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anemia Aortic stenosis Aortic valve Aortic Valve Stenosis - blood Aortic Valve Stenosis - complications Aortic Valve Stenosis - surgery Cohort Studies Confidence intervals Echocardiography Electrocardiography Female Haptoglobin Haptoglobins - metabolism Heart Hemolysis Humans Implantation Male Mercury Middle Aged Mortality Multivariate analysis Patient Readmission Patients Postoperative Complications - epidemiology Prospective Studies Prostheses Prosthetic valves Pulmonary arteries Regression analysis Statistical analysis Stenosis Surgery Transcatheter Aortic Valve Replacement Transplants & implants Treatment Outcome Variables
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Zusammenfassung:	Intravascular hemolysis (IVH) has been identified in patients with surgical prosthetic valves, but few have been reported after transcatheter aortic valve implantation (TAVI). We conducted a prospective analysis of 64 TAVI patients. The hemolysis profiles were collected at baseline and 6 months after TAVI. The echocardiography was performed at baseline and 6 months after TAVI. There are 14 patients (21.9%) with IVH before and 24(37.5%) after TAVI. The serum haptoglobin values before and 6 months after TAVI are 126.7 ± 75.1 vs 86.3 ± 57.1 mg/dl (p
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2017.09.023