Dose-Dependent Effect of Cotinine-Verified Tobacco Smoking on Serum Immunoglobulin E Levels in Korean Adult Males

Dose-Dependent Effect of Cotinine-Verified Tobacco Smoking on Serum Immunoglobulin E Levels in Korean Adult Males

Smoking is one of the risk factors to exacerbate allergic diseases, and it may affect serum immunoglobulin E (IgE) levels. However, few studies have relied on an objective biomarker to examine the effect of tobacco smoking on serum IgE levels. A nationwide cross-sectional study was conducted to exam...

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Veröffentlicht in:Nicotine & tobacco research 2019-05, Vol.21 (6), p.813-817
Hauptverfasser: Dong, Jae-June, Shen, Jay J, Lee, Yong-Jae
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Biomarkers - analysis
Body Mass Index
Cotinine - urine
Cross-Sectional Studies
Dose-Response Relationship, Drug
Female
Humans
Immunoglobulin E - blood
Male
Nutrition Surveys
Republic of Korea - epidemiology
Risk Factors
Smokers
Tobacco Smoking - adverse effects
Tobacco Smoking - blood
Tobacco Smoking - epidemiology
Tobacco Smoking - urine
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Zusammenfassung:Smoking is one of the risk factors to exacerbate allergic diseases, and it may affect serum immunoglobulin E (IgE) levels. However, few studies have relied on an objective biomarker to examine the effect of tobacco smoking on serum IgE levels. A nationwide cross-sectional study was conducted to examine the relationship between urinary cotinine (Ucot) concentrations and IgE levels in 973 males using data from the 2010 Korean National Health and Nutrition Examination Survey (KNHANES). Ucot was classified into four groups based on concentration (ng/mL) as follows: nonsmoker group (Ucot
ISSN:1469-994X
1469-994X
DOI:10.1093/ntr/ntx247