Can NK cells purge HIV sanctuaries?

Can NK cells purge HIV sanctuaries?

A recent study identifies a population of CXCR5 + natural killer (NK) cells patrolling B cell follicles in simian immunodeficiency virus (SIV)-infected African green monkeys that might contribute to the lack of disease progression in this nonpathogenic model.

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Bibliographische Detailangaben
Veröffentlicht in:Nature medicine 2017-11, Vol.23 (11), p.1254-1255
Hauptverfasser: Bunders, Madeleine J, Altfeld, Marcus
Format: Artikel
Sprache:eng
Schlagworte:
631/1647/767/1424
692/699/255/1901
Adipocytes
Animals
Biomedicine
Cancer Research
Care and treatment
Cercopithecus aethiops
Diagnosis
Fatty acids
HIV (Viruses)
HIV-1
Immune system
Immunology
Infectious Diseases
Killer cells
Killer Cells, Natural - virology
Lymph Nodes
Lymphatic system
Metabolic Diseases
Molecular Medicine
Neurosciences
news-and-views
Sanctuaries
Simian Immunodeficiency Virus
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Beschreibung
Zusammenfassung:A recent study identifies a population of CXCR5 + natural killer (NK) cells patrolling B cell follicles in simian immunodeficiency virus (SIV)-infected African green monkeys that might contribute to the lack of disease progression in this nonpathogenic model.
ISSN:1078-8956
1546-170X
DOI:10.1038/nm.4434