Radiopharmaceuticals for imaging and endoradiotherapy of neurotensin receptor‐positive tumors

The neurotensin receptors are overexpressed in various tumor types, especially in highly progressive pancreatic tumors. As this cancer has a poor 5‐year survival prognosis, there is an urgent need to improve early diagnosis and treatment strategies. This review article provides an overview of the la...

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Veröffentlicht in:Journal of labelled compounds & radiopharmaceuticals 2018-03, Vol.61 (3), p.309-325
Hauptverfasser: Maschauer, Simone, Prante, Olaf
Format: Artikel
Sprache:eng
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Zusammenfassung:The neurotensin receptors are overexpressed in various tumor types, especially in highly progressive pancreatic tumors. As this cancer has a poor 5‐year survival prognosis, there is an urgent need to improve early diagnosis and treatment strategies. This review article provides an overview of the latest developments in radiopharmaceuticals for neurotensin receptor‐positive tumors, including peptidic and non‐peptidic radiopharmaceuticals, not only for SPECT and PET but also for endoradiotherapy. This review article provides an overview of the latest developments in radiopharmaceuticals for neurotensin receptor‐positive tumors, including peptidic and non‐peptidic radiopharmaceuticals, not only for SPECT and PET but also for endoradiotherapy.
ISSN:0362-4803
1099-1344
DOI:10.1002/jlcr.3581