Cerebrospinal fluid:serum glucose ratio in the ventricular and lumbar compartments: implications for clinical practice

Background and purpose Calculation of the cerebrospinal fluid:serum glucose (CSF:SGlu) ratio is part of the routine cerebrospinal fluid (CSF) work‐up. Reference values have been defined for lumbar CSF, but are lacking for ventricular CSF. The objective of this study was to investigate whether the CSF:SGlu ratio is similar in lumbar and ventricular compartments, and to determine cut‐off values for CSF:SGlu ratio in ventricular CSF. Methods We included CSF samples that were collected by either lumbar puncture or ventricular drainage, with a red blood cell count