Risk of spontaneous preterm birth in singleton pregnancies conceived after IVF/ICSI treatment: meta‐analysis of cohort studies

ABSTRACT Objective Preterm birth (PTB) is more common in pregnancies conceived by in‐vitro fertilization (IVF) as compared with those conceived naturally. However, the extent to which this is attributed to spontaneous labor or to iatrogenic indications has not been determined. The aim of this study...

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Veröffentlicht in:	Ultrasound in obstetrics & gynecology 2018-01, Vol.51 (1), p.43-53
Hauptverfasser:	Cavoretto, P., Candiani, M., Giorgione, V., Inversetti, A., Abu‐Saba, M. M., Tiberio, F., Sigismondi, C., Farina, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	ART assisted reproductive technologies Birth Cohort analysis Cohort Studies Criteria Data analysis Data processing Female Fertility Fertilization in Vitro - statistics & numerical data Gestation Gestational Age Humans ICSI intracytoplasmic sperm injection In vitro fertilization Incidence Infant, Newborn IVF prematurity Lists Membranes Meta-analysis Morbidity Neonates Pregnancy Pregnancy Outcome Premature birth Premature Birth - epidemiology preterm delivery preterm labor Quality Respiratory distress syndrome Risk Risk Factors Searching Sepsis Sperm Injections, Intracytoplasmic - statistics & numerical data spontaneous preterm birth
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Zusammenfassung:	ABSTRACT Objective Preterm birth (PTB) is more common in pregnancies conceived by in‐vitro fertilization (IVF) as compared with those conceived naturally. However, the extent to which this is attributed to spontaneous labor or to iatrogenic indications has not been determined. The aim of this study was to quantify the risk of spontaneous PTB (sPTB) in singleton pregnancies resulting from IVF or intracytoplasmic sperm injection (ICSI) treatment as compared with that in spontaneously conceived pregnancies. Methods An electronic search of PubMed/MEDLINE, Scopus and Web of Science to September 2017 and manual search of reference lists identified articles comparing the risk of sPTB in IVF/ICSI vs spontaneously conceived singleton pregnancies. Inclusion criteria were singleton conception with IVF/ICSI, PTB defined as delivery before 37 weeks' gestation and cohort design with clear distinction between spontaneous and indicated PTB. The primary outcome was sPTB
ISSN:	0960-7692 1469-0705
DOI:	10.1002/uog.18930