Improved and rapid synthesis of new coumarinyl chalcone derivatives and their antiviral activity
Two closely structurally related coumarins, 4-hydroxy-8-isopropyl-5-methylcoumarin and 4-hydroxy-6-chloro-7-methylcoumarin were acylated at C-3 and further converted to the respective chalcones and two series of eighteen new compounds, which were evaluated for possible antiviral activity.
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| Veröffentlicht in: | Tetrahedron letters 2007-11, Vol.48 (48), p.8472-8474 |
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| creator | Trivedi, Jalpa C. Bariwal, Jitender B. Upadhyay, Kuldip D. Naliapara, Yogesh T. Joshi, Sudhir K. Pannecouque, Christophe C. De Clercq, Erik Shah, Anamik K. |
| description | Two closely structurally related coumarins, 4-hydroxy-8-isopropyl-5-methylcoumarin and 4-hydroxy-6-chloro-7-methylcoumarin were acylated at C-3 and further converted to the respective chalcones and two series of eighteen new compounds, which were evaluated for possible antiviral activity. |
| doi_str_mv | 10.1016/j.tetlet.2007.09.175 |
| format | Article |
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| ispartof | Tetrahedron letters, 2007-11, Vol.48 (48), p.8472-8474 |
| issn | 0040-4039 1873-3581 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_19616995 |
| source | Elsevier ScienceDirect Journals |
| subjects | 4-Hydroxycoumarins Anti-HIV Antiviral Chalcones |
| title | Improved and rapid synthesis of new coumarinyl chalcone derivatives and their antiviral activity |
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