Dendritic Cells Enhance Polyfunctionality of Adoptively Transferred T Cells That Target Cytomegalovirus in Glioblastoma

Median survival for glioblastoma (GBM) remains

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Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2018-01, Vol.78 (1), p.256-264
Hauptverfasser:	Reap, Elizabeth A, Suryadevara, Carter M, Batich, Kristen A, Sanchez-Perez, Luis, Archer, Gary E, Schmittling, Robert J, Norberg, Pamela K, Herndon, 2nd, James E, Healy, Patrick, Congdon, Kendra L, Gedeon, Patrick C, Campbell, Olivia C, Swartz, Adam M, Riccione, Katherine A, Yi, John S, Hossain-Ibrahim, Mohammed K, Saraswathula, Anirudh, Nair, Smita K, Dunn-Pirio, Anastasie M, Broome, Taylor M, Weinhold, Kent J, Desjardins, Annick, Vlahovic, Gordana, McLendon, Roger E, Friedman, Allan H, Friedman, Henry S, Bigner, Darell D, Fecci, Peter E, Mitchell, Duane A, Sampson, John H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Adult Aged Antigen (tumor-associated) Antigens Antitumor activity Biomarkers Brain cancer Brain Neoplasms - therapy Cancer CCL3 protein CD8 antigen CD8-Positive T-Lymphocytes - immunology Cytomegalovirus Dendritic cells Dendritic Cells - immunology Dendritic Cells - metabolism Effector cells Female Glioblastoma Glioblastoma - therapy Humans Immunization Immunotherapy Immunotherapy, Adoptive - methods Lymphocytes Lymphocytes T Male Middle Aged Phosphoproteins - metabolism Pp65 protein Randomization Ribonucleic acid RNA T cell receptors T-Lymphocytes - immunology T-Lymphocytes - transplantation Treatment Outcome Tumor necrosis factor-α Vaccination Viral Matrix Proteins - metabolism γ-Interferon
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Beschreibung
Zusammenfassung:	Median survival for glioblastoma (GBM) remains
ISSN:	0008-5472 1538-7445
DOI:	10.1158/0008-5472.CAN-17-0469