Hyponatraemia and its prognosis in acute heart failure is related to right ventricular dysfunction

Hyponatraemia and its prognosis in acute heart failure is related to right ventricular dysfunction

ObjectivesHyponatraemia is a well-known predictor of clinical outcomes in heart failure (HF). However, the mechanism remains poorly understood. Previous reports suggest that hyponatraemia is related to right HF. We sought to evaluate the association between right ventricular (RV) dysfunction and hyp...

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Veröffentlicht in:Heart (British Cardiac Society) 2018-10, Vol.104 (20), p.1670-1677
Hauptverfasser: Lee, Heesun, Lee, Sang Eun, Park, Chan Soon, Park, Jin Joo, Lee, Ga Yeon, Kim, Min-Seok, Choi, Jin-Oh, Cho, Hyun-jai, Lee, Hae-Young, Choi, Dong-Ju, Jeon, Eun-Seok, Kim, Jae-Joong, Oh, Byung-Hee
Format: Artikel
Sprache:eng
Schlagworte:
Cardiology
Heart failure
Medical diagnosis
Medical prognosis
Mortality
Pulmonary arteries
Pulmonary hypertension
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Zusammenfassung:ObjectivesHyponatraemia is a well-known predictor of clinical outcomes in heart failure (HF). However, the mechanism remains poorly understood. Previous reports suggest that hyponatraemia is related to right HF. We sought to evaluate the association between right ventricular (RV) dysfunction and hyponatraemia, and the impact of this relationship on the prognosis of patients with acute heart failure (AHF).MethodsThis is a nested case–control study of the Korean Acute Heart Failure registry. Among 2935 AHF patients enrolled prospectively and consecutively at four tertiary hospitals in Korea from 2011 to 2014, 116 patients with severe persistent hyponatraemia, defined as serum sodium level
ISSN:1355-6037
1468-201X
DOI:10.1136/heartjnl-2017-312084