Effect of luting agent on the load to failure and accelerated-fatigue resistance of lithium disilicate laminate veneers

•Failure analysis after thermo-cyclic aging showed predominantly wear facets together with chipping or fracture in LVs that were bonded with the regular luting agent while the groups luted with preheated restorative resin composite presented only wear.•Luting of lithium disilicate laminate veneers using a preheated restorative resin composite resulted in significantly higher survival and fracture resistance.•Thermo-cyclic aging showed predominantly chipping and cracks with the regular luting agent and wear in the composite groups. The aim of this study was to investigate the influence of the luting agent on the application of laminate veneers (LVs) in an accelerated fatigue and load-to-failure test after thermo-cyclic aging. Sound maxillary central incisors (N=40) were randomly divided into four groups to receive LVs (Li2Si2O5) that were adhesively bonded: Group CEMF: Adhesive cement (Variolink Esthetic LC), fatigue test; Group CEMLF: Adhesive cement, load-to-failure test; Group COMF: Resin composite (Enamel HFO), fatigue test; Group COMLF: Resin composite, load-to-failure test. The specimens were thermo-mechanically aged (1.2×106 cycles at 1.7Hz/50N, 8000 cycles 5–55°C) and then subjected to either accelerated fatigue (5Hz, 25N increasing after each 500 cycles) or load to failure (1mm/min). Failure types were classified and data analyzed using chi-square, Kaplan Meier survival, Log Rank (Mantel–Cox) and independent-samples t-test. After thermo-mechanical aging, fracture resistance (p