Surgery for Drug-Resistant Epilepsy in Children

In children with drug-resistant epilepsy, the rate of freedom from seizures at 1 year was higher with epilepsy surgery than with medical therapy alone. Most measures of cognitive development were better in the surgery group than in the medical-therapy group.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2017-10, Vol.377 (17), p.1639-1647
Hauptverfasser:	Dwivedi, Rekha, Ramanujam, Bhargavi, Chandra, P. Sarat, Sapra, Savita, Gulati, Sheffali, Kalaivani, Mani, Garg, Ajay, Bal, Chandra S, Tripathi, Madhavi, Dwivedi, Sada N, Sagar, Rajesh, Sarkar, Chitra, Tripathi, Manjari
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adolescents Anterior Temporal Lobectomy - adverse effects Anticonvulsants - therapeutic use Child Child Behavior Child, Preschool Children Clinical trials Cognitive Dysfunction - etiology Convulsions & seizures Drug Resistance Epilepsy Epilepsy - drug therapy Epilepsy - surgery Female Humans Infant Kaplan-Meier Estimate Male Medical research Movement Disorders - etiology Neurosurgery NMR Nuclear magnetic resonance Nuclear medicine Paresis Paresis - etiology Pediatrics Postoperative Complications Quality of Life Seizures Seizures - prevention & control Surgery Surveys and Questionnaires Temporal Lobe - surgery Treatment Outcome
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Beschreibung
Zusammenfassung:	In children with drug-resistant epilepsy, the rate of freedom from seizures at 1 year was higher with epilepsy surgery than with medical therapy alone. Most measures of cognitive development were better in the surgery group than in the medical-therapy group.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa1615335