Cannabis through the looking glass: chemo- and enantio-selective separation of phytocannabinoids by enantioselective ultra high performance supercritical fluid chromatography

Cannabis through the looking glass: chemo- and enantio-selective separation of phytocannabinoids by enantioselective ultra high performance supercritical fluid chromatography

By using the Inverted Chirality Columns Approach (ICCA) we have developed an enantioselective UHPSFC method to determine the enantiomeric excess (ee) of (-)-Δ -THC in medicinal marijuana (Bedrocan®). The ee was high (99.73%), but the concentration of the (+)-enantiomer (0.13 %) was not negligible, a...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2017, Vol.53 (91), p.12262-12265
Hauptverfasser: Mazzoccanti, G, Ismail, O H, D'Acquarica, I, Villani, C, Manzo, C, Wilcox, M, Cavazzini, A, Gasparrini, F
Format: Artikel
Sprache:eng
Schlagworte:
Cannabis
Chirality
Marijuana
Supercritical fluids
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Zusammenfassung:By using the Inverted Chirality Columns Approach (ICCA) we have developed an enantioselective UHPSFC method to determine the enantiomeric excess (ee) of (-)-Δ -THC in medicinal marijuana (Bedrocan®). The ee was high (99.73%), but the concentration of the (+)-enantiomer (0.13 %) was not negligible, and it is worth a systematic evaluation of bioactivity.
ISSN:1359-7345
1364-548X
DOI:10.1039/c7cc06999e