Palladium-Catalyzed Synthesis of 1H‑Indenes and Phthalimides via Isocyanide Insertion

Palladium-Catalyzed Synthesis of 1H‑Indenes and Phthalimides via Isocyanide Insertion

A new and versatile multicomponent domino strategy has been developed for the synthesis of a series of 1H-indene and phthalimide derivatives from simple and readily available starting materials. This process operating under mild conditions shows a broad substrate scope with moderate to excellent yie...

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Veröffentlicht in:Organic letters 2017-11, Vol.19 (21), p.5818-5821
Hauptverfasser: Wang, Xu, Xiong, Wenfang, Huang, Yubing, Zhu, Jiayi, Hu, Qiong, Wu, Wanqing, Jiang, Huanfeng
Format: Artikel
Sprache:eng
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Zusammenfassung:A new and versatile multicomponent domino strategy has been developed for the synthesis of a series of 1H-indene and phthalimide derivatives from simple and readily available starting materials. This process operating under mild conditions shows a broad substrate scope with moderate to excellent yields.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.7b02771