Changes on serum and hepatic lipidome after a chronic cadmium exposure in Wistar rats

•Cadmium LOAEL dose produce changes in serum and hepatic lipidome.•Liver lipidome modification is depending on the accumulation of Cd in the liver of Wistar rats.•Cadmium-exposed rats show features similar to a human metabolic syndrome.•Cadmium exposure provokes an atherogenic phenotype which is evidentiated by small LDL and HDL alterations.•In cadmium LOAEL dose exposition, small HDL subfractions increases and correlate with a hypertriglyceridemia.