Bovine colostrum supplementation does not affect plasma I-FABP concentrations following exercise in a hot and humid environment

Purpose To quantify the impact of a 14-day bovine colostrum (BC) supplementation on intestinal cell damage following exercise in a hot and humid environment. Methods Ten male participants (20 ± 2 years, VO 2max 55.80 ± 3.79 mL kg −1  min −1 , 11.81 ± 2.71% body fat) ran for 46 ± 7.75 min at 95% of v...

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Veröffentlicht in:European journal of applied physiology 2017-12, Vol.117 (12), p.2561-2567
Hauptverfasser: McKenna, Zachary, Berkemeier, Quint, Naylor, Ashley, Kleint, Austin, Gorini, Felipe, Ng, Jason, Kim, Jong-Kyung, Sullivan, Sean, Gillum, Trevor
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Sprache:eng
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Zusammenfassung:Purpose To quantify the impact of a 14-day bovine colostrum (BC) supplementation on intestinal cell damage following exercise in a hot and humid environment. Methods Ten male participants (20 ± 2 years, VO 2max 55.80 ± 3.79 mL kg −1  min −1 , 11.81 ± 2.71% body fat) ran for 46 ± 7.75 min at 95% of ventiliatory threshold in 40 °C and 50% RH following a 14-day double-blinded supplementation with either BC or placebo (Plac). Core temperature, skin temperature, heart rate, and rating of perceived exertion were recorded every 5 min during exercise. Blood was taken pre, post, 1 h, and 4 h post exercise. Intestinal cell damage was assessed via intestinal fatty acid binding protein (I-FABP). Results I-FABP concentrations were similar between conditions at all time points [pre 989.39 ± 490.88 pg ml −1 (BC) 851.35 ± 450.71 pg ml −1 (Plac) post 1505.10 ± 788.63 pg ml −1 (BC) 1267.12 ± 521.51 pg ml −1 (Plac) 1-h, 1087.77 ± 397.06 pg ml −1 (BC) 997.25 ± 524.74 pg ml −1 (Plac) 4-h, 511.35 ± 243.10 pg ml −1 (BC) 501.46 ± 222.54 pg ml −1 (Plac)]. I-FABP was elevated pre to post exercise for both BC (162 ± 50%) and Plac (162 ± 56%) ( p  
ISSN:1439-6319
1439-6327
DOI:10.1007/s00421-017-3743-5